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Rotate sites with each injection to prevent lipohypertrophy, which is the buildup of fibrous tissue at repeatedly injected locations

The 2006-2007 Phase 2 lipodystrophy trial was halted after a participant died

Key safety considerations include: Infection risk : Any injection carries risk of infection if proper aseptic technique is not followed Allergic reactions : Multiple ingredients increase the potential for hypersensitivity Undiagnosed conditions : Self-administration or private clinic use may delay diagnosis of underlying medical conditions Pregnancy and breastfeeding : Safety data for lipotropic formulations in pregnancy is lacking Call 999 immediately if you experience signs of anaphylaxis (difficulty breathing, facial/tongue swelling, collapse) after an injection

Also, if you have to drink more alcohol to feel its effects, you may have developed a tolerance, which can also be early signs of an alcohol use disorder